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UProC: tools for ultra-fast protein domain classification
2014
Computer applications in the biosciences : CABIOS
Motivation: With rapidly increasing volumes of biological sequence data the functional analysis of new sequences in terms of similarities to known protein families challenges classical bioinformatics. Results: The ultrafast protein classification (UProC) toolbox implements a novel algorithm ('Mosaic Matching') for large-scale sequence analysis. UProC is by three orders of magnitude faster than profile-based methods and in a metagenome simulation study achieved up to 80% higher sensitivity on
doi:10.1093/bioinformatics/btu843
pmid:25540185
pmcid:PMC4410661
fatcat:ykeqts7pcnduvjgzuhdhvlsy4q