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Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent
We have developed Si-based agent which can generate a large amount of hydrogen. Si-based agent continues generating hydrogen for more than 24 h by the reaction with water under conditions similar to those in bowels, i.e., pH8.3 and 36 °C, and generates ~400 mL hydrogen. To investigate beneficial effects for diseases associated with oxidative stress, Si-based agent is administered to remnant kidney rats and Parkinson's disease mice. Rats are fed with control or Si-based agent-containing diet fordoi:10.1038/s41598-020-62755-9 pmid:32246095 fatcat:ey4vra7xrvhkbfkamknwpzr23u