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Automatic pain recognition from facial expressions is a challenging problem that has attracted a significant attention from the research community. This article provides a comprehensive analysis on the topic by comparing some popular and Off-the-Shell CNN (Convolutional Neural Network) architectures, including MobileNet, GoogleNet, ResNeXt-50, ResNet18, and DenseNet-161. We use these networks in two distinct modes: stand alone mode or feature extractor mode. In stand alone mode, the modelsdoi:10.3390/electronics10161926 fatcat:i2ngi5vmc5f2vczgitegwsf67e