Unusual axillary metastasis of recurrent nasopharyngeal cancer

Deng-Yu Kuo, Min-Hsiang Chang, Shan-Ying Wang, Pei-Ying Hsieh, Pei-Wei Shueng
2017 Medicine  
Nasopharyngeal carcinoma (NPC) has a high propensity of metastasis. The most commonly described sites of distant metastasis are the bones, lungs, and liver, whereas axillary metastasis is seldom reported. We hereby present the case of a 66-year-old man with NPC, cT2N2M0, at diagnosis. He had completed chemoradiotherapy and been disease-free for 7 years. After that period, late recurrence in the form of a solitary axillary lymph node metastasis was detected and confirmed by core-needle biopsy.
more » ... e lesion was chemoresistant but responded to salvage radiotherapy at a dose of 65 Gy in 21 fractions. Post-radiotherapy positron emission tomography scan showed no evidence of disease. We suggested that long-term follow-up of NPC patients is important because a late relapse may occur at an unusual site. Aggressive management of solitary metastasis may achieve good outcome.
doi:10.1097/md.0000000000006854 pmid:28514301 pmcid:PMC5440138 fatcat:ou5kazstkzghzevmlz4sj3dyrm