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Purpose: The purpose of this study is to differentiate neuromyelitis optica and its related disorders. Materials and Method: A retrospective single site study of 104 patients from July 2014 to October 2017 with optic neuritis and/or myelitis was done. After history taking and complete ocular examination, neurological examination, cerebrospinal fluid examination, magnetic resonance imaging and aquaporin 4 antibody testing, patients were categorised as neuromyelitis optica, multiple sclerosis anddoi:10.7869/djo.499 fatcat:cxg6fidejbfopdx7v4fnsh4o24