Response to thalidomide in scleromyxedema
Respuesta a la talidomida en escleromixedema

María Florencia Pascualini, Guadalupe Caballero Escuti, Enrique Valente, María Kurpis, Alejandro Ruiz Lascano
2013 Medicina (Buenos Aires)  
The scleromyxedema is a rare condition characterized by hyperproliferation of fibroblasts with increased dermal deposition of mucin and frequently associated with monoclonal gammopathy of undetermined significance. Various treatments have been reported, with inconsistent results. In addition, the rarity of the disease and the lack of randomized controlled trials results in treatment options derived from anecdotal reports. We describe the case of a 52 year-old female patient diagnosed with
more » ... iagnosed with scleromyxedema who developed a monoclonal gammopathy, with adequate response to thalidomide. The follow up of these patients is important due to the risk of progression to multiple myeloma and complications related to systemic treatments.
pmid:23732202 fatcat:epevyxlvrjfeph7atnqxbjz45q