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PHYTOCHEMICAL SCREENING AND ANTIDIABETIC ACTIVITY OF DIFFERENT LEAF EXTRACTS FROM LOTUS (NELUMBO NUCIFERA GAERTN.) IN STREPTOZOTOCIN INDUCED MICE

Ruth Mayana Rumanti, Marline Nainggolan, Urip Harahap
2017 Asian Journal of Pharmaceutical and Clinical Research  

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Objective: The present study is to evaluate the antidiabetic activity of various extract of Lotus (Nelumbo nucifera Gaertn.) leaf using hexane, ethyl acetate, and ethanol organic solvent.Methods: Standard phytochemical screening method and streptozotocin induced diabetic mice.Result: The phytochemical screening showed only ethyl acetate of lotus leaf extract contains the flavonoids. The ethyl acetate lotus leaf extract (dose level 150 mg/kg) showed a significant reduction of the blood
more » ... nclusion: The ethyl acetate extract of lotus leaf (N. nucifera Gaertn.) had the hypoglycemic effect on diabetic induced mice.
doi:10.22159/ajpcr.2017.v10i12.20888 fatcat:aq2te4x4obhrhprcmx4izpzwfu
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Ruth Mayana Rumanti, Marline Nainggolan, Urip Harahap. "PHYTOCHEMICAL SCREENING AND ANTIDIABETIC ACTIVITY OF DIFFERENT LEAF EXTRACTS FROM LOTUS (NELUMBO NUCIFERA GAERTN.) IN STREPTOZOTOCIN INDUCED MICE." Asian Journal of Pharmaceutical and Clinical Research 10.12 (2017) 190