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The Roundabout (Robo) receptors have been intensively studied for their role in regulating axon guidance in the embryonic nervous system, whereas a role in dendritic guidance has not been explored. In the adult giant fiber system of Drosophila, we have revealed that ectopic Robo expression can regulate the growth and guidance of specific motor neuron dendrites, whereas Robo2 and Robo3 have no effect. We also show that the effect of Robo on dendritic guidance can be suppressed by Commissurelessdoi:10.1523/jneurosci.22-08-03117.2002 pmid:11943815 pmcid:PMC6757528 fatcat:g3fk44koqvge5l7cgcsii6boju