Inflammation in Atherosclerosis and Implications for Therapy

R. Paoletti
2004 Circulation  
Atherosclerosis is now understood to be a disease characterized by inflammation that results in a host of complications, including ischemia, acute coronary syndromes (unstable angina pectoris and myocardial infarction), and stroke. Inflammation may be caused by a response to oxidized low-density lipoproteins, chronic infection, or other factors; and markers of this process, such as C-reactive protein, may be useful to predict an increased risk of coronary heart disease. Thus, we believe that
more » ... we believe that inflammatory processes may be potential targets of therapy in preventing or treating atherosclerosis and its complications. (Circulation. 2004;109[suppl III]:III-20 -III-26.)
doi:10.1161/01.cir.0000131514.71167.2e pmid:15198962 fatcat:v6onx37vgfendjdwxga4asr2qa