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Nature is a superb source of inspiration when it comes to the development of biomaterials. Proteins, an exquisite asset virtually involved in all biological functions, are envisioned as a biomaterial due to their ability to be chemically modified. Owing to the rich chemical repertoire provided by the side chains and C-/N-terminus present in their backbone, scientists are pursuing chemical ways to upgrade isolated proteins, while maintaining their biological activity or relevant structuraldoi:10.1016/j.bbiosy.2021.100010 fatcat:5x4vkbzbpbbpll5eo2jpiflmeq