OL-019 Effect of scilencing connective tissue growth factor on rats TGF-β/Smads signal

G.M. Li, D.G. Li, Q. Xie, Y. Shi, S. Jiang, Y.X. Jin
2008 International Journal of Infectious Diseases  
S41 to normal control group (P < 0.01); S0 1 group and the normal control group were no significant difference (P > 0.05); S0 1 group and S2 4 group were significantly different (P < 0.01); S0 1 group and end stage of cirrhosis group were significantly different (P < 0.01); S2 4 group and end stage of cirrhosis group were significantly different (P < 0.01). 2. The correlation analysis between serum HBV DNA and liver fibrosis stage. There was no correlation between HBV DNA level and liver
more » ... s stage (r = 0.140, P > 0.05). 3. The correlation analysis between serum HBV DNA and AT1R mRNA. There was no correlation between HBV DNA level and AT1RmRNA (r = 0.014, P > 0.05). HE×10 Masson×10 Case 1, Pre-treatment; G2, S3. Case 1, Post-treatment; G3, S4. HE×10 Masson×10 Case 2, Pre-treatment; G4, S3 4. Objective: To investigate the effect of small interfering RNA targeting connective tissue growth factor (CTGF) on rats TGF-b/Smads signal.
doi:10.1016/s1201-9712(09)60116-8 fatcat:zlbo3cw3wfcjtdydhb3j2awq5y