Almagate interference in breath test results for the diagnosis of Helicobacter pylori infection

Carles Pons, Sandra Maisterra, Silvia Salord, Angels Pla, David Asensio, Francisco Javier Fernández, Gerard Traveria, Guillem Roura
2014 Revista Espanola de Enfermedades Digestivas  
Infection by Helicobacter pylori is common and affects both genders at any age. The 13C-urea breath test is a widely used test for the diagnosis of this infection. However, multiple drugs used for the treatment of Helicobacter pylori infection symptoms have interactions with this breath test that generate false negative results. This observational study was to assess the potential interaction between almagate and the breath test. Thirty subjects on almagate therapy who underwent a breath test
more » ... ent a breath test were included. If the result was negative, almagate was withdrawn for a month and the breath test was then repeated. In general, 51.9 % of assessed subjects had a negative result after the first test, and 100 % of these also had a negative result after the second test. It was concluded that the use of almagate does not interfere in breath test results. These results provide a drug therapy option for the treatment of symptoms associated with Helicobacter pylori infection during the diagnostic process.
pmid:25490163 fatcat:nvtyh474znfd7aa4vusnxcovoi