Biomimetic coating of apatite/collagen composite on Poly L-lactic Acid facilitates cell seeding

Yun Chen, A.F.T. Mak, Min Wang, Jiashen Li
2005 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference  
Collagen and apatite were co-precipitated as a composite coating on poly L-lactic acid (PLLA) in an accelerated biomimetic process. The coating formed on PLLA films after 24 hours incubation was characterized. Saos-2 osteoblast-like cells were used to evaluate the cell seeding on this biomimetic composite coating. It was shown that cell seeding on PLLA films with the composite coating was greatly improved. PLLA coated with submicron collagen fibrils and submicron apatite paticulates can facilitate bone tissue engineering.
doi:10.1109/iembs.2005.1615361 pmid:17281131 fatcat:qbc5fddmerahlojqjfyxhtr6zm