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Growing number of studies report on the improved sensitivity of various imaging modalities in detecting abnormalities within tumours. Surface enhanced Raman scattering (SERS) microscopy is a novel optical imaging technique which is advantageous in terms of greater multiplexing capability, minimal or no photobleaching of the Raman reporters, better spatial resolution and low signal-to-noise ratio within complex biological environment. For the enhancement of the Raman vibrational signal in SERSdoi:10.4172/2157-7439.s6-002 fatcat:ioiewg7hpvbv7at4bxns76h4ka