Maternal sepsis caused by Clostridium perfringens: A Case Report

S. S. Jayasena, W. D. Galagedara, S. Pathirage, S. Akmeemana, N. S. Chandrasiri
2021 Sri Lankan Journal of Infectious Diseases  
Anaerobic pathogens are rarely isolated from infections due to many reasons including difficulties in accessing anaerobic transport media and anaerobic culture facilities. Of anaerobic pathogens isolated from uterine infections, Clostridium perfringens is reported more than other anaerobes. We describe a case of maternal sepsis following incomplete miscarriage without trauma in a previously healthy female. Her initial percutaneous blood culture signaled positive, and Gram stain revealed Gram
more » ... itive large bacilli which failed to grow on standard culture media after 48 hours of aerobic incubation. However, a pure growth of C. perfringens was isolated after anaerobic incubation. The patient improved rapidly following evacuation and antibiotic combination of ceftriaxone and doxycycline. The usefulness of anaerobic culture, especially where anaerobic pathogens are likely to be the causative agents, is illustrated in this case report.
doi:10.4038/sljid.v11i2.8405 doaj:ccd857f98b294f40bb956f56c5d3a1a1 fatcat:52jzzkqco5b7vhkbmoaqqcr7yq