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Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
4-(4'-quinazolin-ylamino) phenyl-4-(N,N-dimethylamino) phenyl propenyl ketone with total yield of 68.0% was synthesized with 2-aminobenzonitrile and N,N-dimethylformamide dimethyl acetal as a starting material, the synthesis of N-(2-cyanophenyl)-N,N-dimethyl formamidine, and then amino acetophenone to form a ring, and finally reaction with formaldehyde dimethylaminobenzaldehyde. The experimental conditions were optimized. The results showed that: Intermediate 1 was synthesized bydoi:10.2991/ic3me-15.2015.61 fatcat:ux2hxfdvkjfrpd7inidefphmwa