Although little is known on the function of γδ T lymphocytes, there is increasing evidence that γδ T lymphocytes are early responders and modulators of immune responses against pathogens and cytokines such as IL-2, IL-7, IL-15 and TNF-α. To study the role TNF-α on γδ T lymphocytes, we cloned bovine TNF-α. Sequence analysis revealed that a new allele form of bovine TNF-α was cloned which has 3 additional nucleotide sequences as well as 3 nucleotide substitutions compared with previously reported

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... bovine TNF-α. Further studies are needed to document the functional significance of a new allele form of TNF-α in cattle.