SL2: an interactive webtool for modeling of missing segments in proteins

Jochen Ismer, Alexander S. Rose, Johanna K. S. Tiemann, Andrean Goede, Robert Preissner, Peter W. Hildebrand
2016 Nucleic Acids Research  
SuperLooper2 (SL2) (http://proteinformatics.charite. de/sl2) is the updated version of our previous webserver SuperLooper, a fragment based tool for the prediction and interactive placement of loop structures into globular and helical membrane proteins. In comparison to our previous version, SL2 benefits from both a considerably enlarged database of fragments derived from high-resolution 3D protein structures of globular and helical membrane proteins, and the integration of a new protein
more » ... The database, now with double the content, significantly improved the coverage of fragment conformations and prediction quality. The employment of the NGL viewer for visualization of the protein under investigation and interactive selection of appropriate loops makes SL2 independent of third-party plug-ins and additional installations.
doi:10.1093/nar/gkw297 pmid:27105847 pmcid:PMC4987885 fatcat:ypb3if6c2zgjnl3f3bw6q733xy