Dr. Syed Hammad Ali, Dr. Kainat Nazir, Dr. Masooma Ayesh
2020 Zenodo  
Aim: To investigate the sensitivity pattern of Staphylococcus aureus isolates obtained from clinical samples, including urine and wounds, to commonly used antibiotics. Methods: This prospective study has been conducted in the Medicine and Surgical department of Benazir Bhutto hospital Rawalpindi for one year duration from March 2019 to March 2020. Clinical samples including urine, wound swab were taken from patients with informed consent and were analyzed at the Department of Pathology. Samples
more » ... Pathology. Samples were aerobically cultured in blood agar and in cystine lactose electrolyte deficient (CLED) agar. The isolates were identified by motility test, colony morphology, and Gram staining and biochemical tests. Amoxicillin, co-amoxiclav, cefradine, cefuroxime, sparfloxacin, meron, tinem and linzolid discs were used. Results: A total of 150 cases contained 75 urine and wound swabs each. There were 85 men and 65 women. The sensitivity pattern in wound swabs was; Tinem (98.7%), Linzolid (97.3%), Meronem (94.7%), Co-Amoxiclav (93.3%), Cephradnie (90.7%), Cefuroxime (86.7%), Amoxicillin (82.7%) and Sparfloxacin (80%). In the urine sample, S. aureus was sensitive to Tinem (94.7%), Meronem (93.3%), Sparfloxacin (93.3%), Linzolid (90.7%), Cefuroxime (86.7%), Co -Amoxiclave (80%), Amoxicillin (69.4%), Cephradine. Conclusion: Staphylococcus aureus in wound and urine culture is almost always sensitive to the antibiotic Tinem. Sensitivity to cephradine in wound culture is twice as high as in urine culture. Keywords: S. Aureus, Sensitivity, Gram positive, Antibiotics
doi:10.5281/zenodo.3896643 fatcat:g7qykapx7jhd3nraiecqgvvxwm