Pictalignans D-F, three new neolignan derivatives from Selaginella picta

Fei Cheng, Zhen-Xing Zou, Ping-Sheng Xu, Shui-Han Zhang, Yan Zhang, Cai-Ping Yao, Kang-Ping Xu, Gui-Shan Tan
2019 Figshare  
Three new neolignan derivatives (1–3), together with three known isolariciresinol derivatives (4–6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-22 cells induced by L-Glutamate in vitro. All compounds displayed potent protective effect on HT-22 cells.
doi:10.6084/m9.figshare.7608956.v1 fatcat:6b5t4iaq3vdjlirygaswzplhxu