Green synthesis of quinoline-4-carboxylic acid derivatives using silica sulfuric acid as an efficient catalyst

N. G. Salunkhe, N. V. Thakare, C. A. Ladole, A. S. Aswar
2015 Zenodo  
Department of Chemistry, Sant Gadge Baba Amravati University, Amravati-444 602, Maharashtra, India E-mail : aswaranand@gmail.com Manuscript received online 22 October 2014, accepted 16 December 2014 Quinoline-4-caboxylic acid derivatives were synthesized in moderate to high yields via one-pot three components Doebner reaction of pyruvic acid, aldehydes and anilines in the presence of silica sulfuric acid as an efficient catalyst, under very mild conditions with excellent yields. The notable
more » ... ntages of this protocol are work-up procedure is easy and the catalyst can be recovered by simple filtration and reused.
doi:10.5281/zenodo.5599012 fatcat:3zobftvt7rdx5lqu2kqfidptgq