Introduction. Population aging is a medical and social problem that receives special attention from the governments of developed and developing countries. The research objective was to assess the content of biologically active substances in fruits and leaves of Vitis amurensis Rupr. harvested in the Amur Region. The authors analyzed the phenolic profile, anti-radical potential, and the possibility of their complex processing for further use in functional foods. Study objects and methods. The

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... hor reviewed ten years of domestic and foreign publications, standards, and legislative documents. The research featured leaves and fruits of Vitis amurensis Rupr., collected in various areas of the Amur Region. The composition of biologically active substances was analyzed using potentiometric, titrimetric, colorimetric, and photocolorimetric methods, as well as the method of X-ray fluorescence analysis. Results and discussion. The sugar content in fruits of Vitis amurensis Rupr. was 11.97%, in leaves – 1.14%. In the fruits, the maximum calcium content was 62.57 ± 0.01 mg/100 g. Potassium content was the highest in the leaves (0.105 ± 0.004 mg/100 g). Caftaric acid had the largest content in leaves and fruits: 4.97 ± 0.01 and 125.69 ± 0.32 mg/kg, respectively. The highest content of resveratrol was found in fruits (148.16 ± 1.40 mg/kg), while in leaves it was only 9.87 ± 0.61 mg/kg. Likewise, fruits demonstrated the maximum content of flavonols: quercetin – 136.21 ± 5.60 mg/kg, kaempferol – 1.19 ± 0.01 mg/kg. Conclusion. Vitis amurensis Rupr. is a promising source of bioactive compounds. Due to its comprehensive phytochemical assessment, it can find wider application in nutritive sciences, cosmetic industry, and food combinatorics. Fruits and leaves of Vitis amurensis Rupr. proved to possess a high antioxidant activity due to polyphenols, resveratrol, B vitamins, and vitamin C.