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Estimation of self-sustained activity produced by persistent inward currents using firing rate profiles of multiple motor units in humans
2020
Journal of Neurophysiology
Persistent inward calcium and sodium currents (IP) activated during motoneuron recruitment help synaptic inputs maintain self-sustained firing until de-recruitment. Here, we estimate the contribution of the IP to self-sustained firing in human motoneurons of varying recruitment threshold by measuring the difference in synaptic input needed to maintain minimal firing once the IP is fully activated compared with the larger synaptic input required to initiate firing prior to full IP activation.
doi:10.1152/jn.00194.2020
pmid:32459555
fatcat:m3iaa2d3pjfspj6uxbskwrxj7m