Novel 2',5'-oligoadenylates synthesized in interferon-treated, vaccinia virus-infected cells

A P Rice, S M Kerr, W K Roberts, R E Brown, I M Kerr
1985 Journal of Virology  
2-5A[ppp(A2'p),A] and related materials accumulate to greater than micromolar concentrations in vaccinia virus-infected HeLa cells and in interferon-treated, vaccinia-infected HeLa, CVI, and L929 cells even when virus replication is not inhibited. A variably complex mixture of authentic 2-5A (n = 2 to 4), nonphosphorylated cores [(A2'p)nA; n = 2 to 5], and additional compounds of unknown structure was observed.
doi:10.1128/jvi.56.3.1041-1044.1985 fatcat:wj4bpvxbdrf4tfjg52ufivxsrm