Water-clear cell adenoma of the mediastinal parathyroid gland

Deniz Arik, Emine Dundar, Evrim Yilmaz, Cumhur Sivrikoz
2013 Türk Patoloji Dergisi  
Water-clear cell adenoma of the parathyroid gland is a rare neoplasm that consists of cells with abundant clear-pink cytoplasm. There have only been 19 cases reported in the English literature. here we report a case of water-clear cell adenoma of the mediastinal parathyroid gland. A 70-year-old male patient presented to the hospital with back pain and a mediastinal mass 6 cm in size was detected. After excision and microscopic evaluation, uniform, large clear cells with fine cytoplasmic
more » ... cytoplasmic vacuolization, without nuclear atypia, and arranged in solid and acinar patterns were revealed. The cells formed nests that were separated by fine fibrovascular septae and stained positively with anti-parathyroid hormone. To the best of our knowledge, this has not been previously reported in this location. In the differential diagnosis of clear cell lesions of the mediastinum, water-clear cell parathyroid adenoma should be considered.
doi:10.5146/tjpath.2017.01407 pmid:28832084 fatcat:2k6z3mvxgfgjzjgossfjyvhjze