Neuropeptide Y reduces migration capacity of human choriocarcinomacell line by altering oxidative/antioxidative status

Miloš MATIĆ, Milica PAUNOVIĆ, Branka OGNJANOVIĆ, Andraš ŠTAJN, Zorica SAIČIĆ
2017 Turkish Journal of Biology  
H 2 O 2 ) and molecules of the antioxidant defense system (reduced glutathione and oxidized glutathione), while the levels of intracellular nitrites (indicators of NO) and cell migration index were significantly decreased in trophoblast cells treated with NPY (both at 24 h and 72 h of exposure) compared to the control cells. These results suggest that NPY may significantly contribute to reduced migration capacity of trophoblast cells by generating oxidative stress and reducing the
more » ... g the bioavailability of NO.
doi:10.3906/biy-1606-73 fatcat:4nehky7e55gi5heeguqbbgbwbe