Precision determinations of Standard Model (SM) Electro-Weak (EW) parameters at the Large Hadron Collider (LHC) are dominated by uncertainties due to Parton Distribution Functions (PDFs). Reweighting and profiling techniques are routinely employed to treat this. We explore approaches based on combining measurements of charged current and neutral current Drell-Yan (DY) asymmetries to improve PDF uncertainties. We present the results of a numerical analysis performed with the open-source platform

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... xFitter. PDF uncertainties are examined for lepton-charge and forward-backward asymmetries in regions of transverse and invariant masses near the vector-boson peak, based on LHC Run III and HL-LHC luminosity scenarios. We discuss the complementarity of the asymmetries in reducing PDF uncertainties in observables relevant to both SM and Beyond the SM (BSM) physics.