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FRI0458 The onset, clinical course and outcomes of ssc- overlap with pm/dm or ra (SSC-PM/DM AND SSC-RA)
FRIDAY, 15 JUNE 2018
death. These parameters had been defined by expert nominal group technique. Methodologically, two main limitations had to be addressed: 1 the problem of missing data and 2 the low number of events, which prohibits the simultaneous exploration of a large set of predictors in a regression model. We addressed these issues by (a) imputing multiple predictors based on different algorithms (multiple imputation), and (b) using least absolute shrinkage and selection operator (LASSO) regression for 42doi:10.1136/annrheumdis-2018-eular.5134 fatcat:lktqmem7s5ez7bxxnfw62v4lqu