English Session-Keynote Lecture Abstract, Oral Abstract
Arerugi = [Allergy]
2) ) Background:Barley is widely consumed in Asia, but studies on barley allergy are limited to few case reports about hypersensitivity reactions to beer. Objectives: This study aimed to identify the clinical and laboratory findings of barley allergy in Korean children. Methods:Forty-four participants with a history of ingesting barley who underwent serum specific IgE to barley(barley-sIgE)assay at the Department of Pediatrics in Ajou University Hospital were enrolled through a retrospective
... iew of medical records from March 2008 to February 2018. The demographic profiles, clinical symptoms, and laboratory findings of the patients were evaluated. Results:Twenty-two patients had clinical barley allergy (B-allergic group) , and 22 were atopic controls without allergic reactions to barley(B-tolerant group) . In the B-allergic group, the cutaneous system (90.9%)was most commonly affected, and anaphylaxis was observed in 31.8% of the patients. The median levels of barley-sIgE in the B-allergic group and B-tolerant group were 11.04 and 0.30 kUA/L, respectively, with an optimal cutoff level of 1.24 kUA/L. The median barley-sIgE levels of the Anaphylactic and Non-anaphylactic groups were 21.00 and 2.07 kUA/L, respectively, with an optimal cutoff level of 5.30 kUA/L. A positive correlation was found between the serum levels of barley-sIgE and wheat-sIgE in the B-allergic group with wheat allergy. Conclusions:Approximately 32% of children with barley allergy experienced anaphylaxis. The optimal cut-off level of barley-sIgE that can be used in distinguishing the B-allergic group from the B-tolerant group was 1.24 kUA/L.