Hesperidin as a preventive resistance agent in MCF-7 breast cancer cells line resistance to doxorubicin

Rifki Febriansah, Dyaningtyas Putri, Sarmoko Sarmoko, Nunuk Nurulita, Edy Meiyanto, Agung Nugroho
2020 Figshare  
Hesperidin has antiproliferative effect on MCF-7 cells. This study aimed to determine the effect of hesperidin on MCF-7 and MCF-7/Dox cells. The study demonstrated cytotoxicity of hesperidin, apoptosis induction and Pgp expression, when given singly and combination with doxorubicin. The results will be basic research in order to explore hesperidin as an alternative to co-chemotherapy agent in breast cancer therapy.
doi:10.6084/m9.figshare.11858310.v2 fatcat:wqzepnvguveuppkd6t4ia4frcq