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Nanomaterials are showing great promise in their utility for biomedical applications, in areas such as drug delivery, diagnostics and image contrast enhancement. Nanoparticlebased formulations have demonstrated enhanced efficacy and decreased toxicity in comparison to conventional drugs. Comprehensive preclinical characterization of is a critical step in commercialization of nanoparticle-based formulations      . Nanoparticle formulations are often comprised of variousdoi:10.1017/s1431927610060149 fatcat:lkqw2v5z7rdy3ngxrq6hutiv2i