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Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids
2006
Oncology Reports
Multicellular Tumor Spheroid (MTS) represents a three-dimentional structural form of tumors in laboratory conditions, and it has the characteristics of avascular micrometastases or intervascular spaces of big tumors. Recent studies indicate that extracellular matrix (ECM) proteins play a critical role in tumor metastasis, therefore normal and cancer cells require an ECM for survival, proliferation and differentiation. Doxorubicin and Docetaxel are widely used in the therapy of breast cancer, as
doi:10.3892/or.15.2.335
fatcat:lgofiywp4beczmb5lm2ypg3nhm