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Identifying wrong assemblies in de novo short read primary sequence assembly contigs
2016
Journal of Biosciences
With the advent of short-reads-based genome sequencing approaches, large number of organisms are being sequenced all over the world. Most of these assemblies are done using some de novo short read assemblers and other related approaches. However, the contigs produced this way are prone to wrong assembly. So far, there is a conspicuous dearth of reliable tools to identify mis-assembled contigs. Mis-assemblies could result from incorrectly deleted or wrongly arranged genomic sequences. In the
doi:10.1007/s12038-016-9630-0
pmid:27581937
fatcat:qdto3h2aunch3j7uasm7evpghe