Advances in long non-coding RNA in chemotherapeutic resistance of hepatocellular carcinoma

Gui-Ju TANG, Yuan TIAN, Ji-Ting WANG, Song SU, Min SONG, Ya-Ling LI
2020 Medical Journal of Chinese People's Liberation Army  
Hepatocellular carcinoma (HCC), as a global malignant tumor with high morbidity and mortality, has seriously endangered human health. In the treatment of HCC, chemotherapy resistance is the knotty problem. Long non-coding RNA (lncRNA), as a new multifunctional molecule with complex mechanisms, plays a role in the biological processes of HCC, such as development, progression, invasion and migration, and participates in the complex mechanism of drug resistance through abnormal regulation of gene
more » ... regulation of gene expression. In this paper, to seek for the new method for solving the chemotherapeutic resistance of HCC based on the research of lncRNA, the effect and mechanism of lncRNA on chemotherapeutic resistance of HCC were summarized. DOI: 10.11855/j.issn.0577-7402.2020.05.15
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