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Multiscale Cancer Modeling and In Silico Oncology: Emerging Computational Frontiers in Basic and Translational Cancer Research
2013
Journal of Bioengineering and Biomedical Sciences
Inferring network topologies: involves identification of interaction motifs such as feedback or feed forward loops, methods to infer bistability and robustness, construction and curation of Boolean networks and directed graphs using statistical inference techniques, information theory, and Bayesian analysis [13] . Inferring gene and protein interaction networks: involves applying dimensionality reduction techniques such as principal component analysis, hierarchical clustering and tree
doi:10.4172/2155-9538.1000e114
pmid:30740263
pmcid:PMC6368085
fatcat:ybzcgmqeajerdbjrq34vp7tg3i