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Local, cell-nonautonomous feedback regulation of myosin dynamics patterns transitions in cell behavior: a role for tension and geometry?
2013
Molecular Biology of the Cell
How robust patterns of tissue dynamics emerge from heterogeneities, stochasticities, and asynchronies in cell behavior is an outstanding question in morphogenesis. A clear understanding of this requires examining the influence of the behavior of single cells on tissue patterning. Here we develop single-cell manipulation strategies to uncover the origin of patterned cell behavior in the amnioserosa during Drosophila dorsal closure. We show that the formation and dissolution of contractile,
doi:10.1091/mbc.e12-12-0868
pmid:23741052
pmcid:PMC3727928
fatcat:s2oxw5zdbvdopayb6e2nvotf4m