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Treacher Collins Syndrome (TCS) is a dominantly inherited autosomal disease which limited to head and neck movement. In management of difficult airways which is seen in patients with TCS, the direct laryngoscope, video-laryngoscope (VL), and fiber-optic laryngoscope (FOB) were successfully utilized. No study that was indicated the successful execution of nasotracheal intubation on a patient with TCS by using C-MAC video-laryngoscope was found in literature review. In this case report, we aimeddoi:10.5455/medscience.2017.06.8629 fatcat:ypqycvib3ng2fkvynwqiil7gym