Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study

A. Nanri, T. Mizoue, M. Noda, Y. Takahashi, M. Kato, M. Inoue, S. Tsugane
2010 American Journal of Clinical Nutrition  
Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, which is a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear. Objective: We prospectively investigated the association between white rice intake and risk of type 2 diabetes. Design: Participants were 25,666 men and 33,622 women aged 45-75 y who participated in the second survey of the Japan Public
more » ... th Center-Based Prospective Study and who had no prior history of diabetes. We ascertained food intake by using a validated 147-item food-frequency questionnaire. Odds ratios of self-reported, physician-diagnosed type 2 diabetes over 5 y were estimated by using logistic regressions. Results: A total of 1103 new cases of type 2 diabetes were selfreported. There was a significant association between rice intake and an increased risk of type 2 diabetes in women; the multivariateadjusted odds ratio for the highest compared with lowest quartiles of rice intake was 1.65 (95% CI: 1.06, 2.57; P for trend = 0.005). In men, the association was unclear, although there was a suggestion of a positive association in persons who were not engaged in strenuous physical activity (P for trend = 0.08). Conclusions: Elevated intake of white rice is associated with an increased risk of type 2 diabetes in Japanese women. The finding that is suggestive of a positive association of rice intake in physically inactive men deserves further investigation. Am J Clin Nutr
doi:10.3945/ajcn.2010.29512 pmid:20980490 fatcat:cbazhkc4v5alfivwu2r2iya3la