Acute otitis media (AOM) is one of the most common diseases in infancy and early childhood, resulting in parents frequently seeking medical assistance for their child. Antibiotics are often prescribed. Decongestants and antihistamines have commonly been recommended by clinicians with the aim of targeting the middle ear effusion that develops in AOM. The first line antibiotic treatment, if warranted, is amoxicillin. If the bacteria is resistant, then amoxicillin-clavulanate or another penicillin

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... derivative plus beta lactamase inhibitor is second line. Five days of treatment has been found to be as effective as ten days in otherwise healthy children.Co-amoxiclave has been found to have more clinical efficacy as compared to azithromycin.