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Test-retest reproducibility of quantitative binding measures of [ 11 C]Ro15-4513, a PET ligand for GABA A receptors containing alpha5 subunits
2017
NeuroImage
Alteration of γ-aminobutyric acid "A" (GABAA) receptor-mediated neurotransmission has been associated with various neurological and psychiatric disorders. [11C]Ro15-4513 is a PET ligand with high affinity for α5-subunit-containing GABAA receptors, which are highly expressed in limbic regions of the human brain (Sur et al., 1998). We quantified the test-retest reproducibility of measures of [11C]Ro15-4513 binding derived from six different quantification methods (12 variants).
doi:10.1016/j.neuroimage.2016.12.038
pmid:28292717
pmcid:PMC5440177
fatcat:2dmkhunborfibd2cfdewfbtgpu