A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf
.
Predicting protein interaction sites from residue spatial sequence profile and evolution rate
2005
FEBS Letters
This paper proposes a novel method that can predict protein interaction sites in heterocomplexes using residue spatial sequence profile and evolution rate approaches. The former represents the information of multiple sequence alignments while the latter corresponds to a residueÕs evolutionary conservation score based on a phylogenetic tree. Three predictors using a support vector machines algorithm are constructed to predict whether a surface residue is a part of a protein-protein interface.
doi:10.1016/j.febslet.2005.11.081
pmid:16376878
fatcat:ysihizesqjgrbejt5fqzujqdp4