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Gene expression profiling of oral submucous fibrosis using oligonucleotide microarray
1994
Oncology Reports
Although oral submucous fibrosis (OSF) is the most common precancerous lesion of the oral cavity in Southeast Asia where the habit of betel quid (BQ) chewing is popular, its molecular biological properties are largely unknown. The aim of this study was to identify the genes responsible for its pathogenesis and malignant transformation using oligonucleotide microarray. The expression profiles of 14,500 genes in human oral submucous fibrosis and normal control were analyzed using Affymetrix U133A
doi:10.3892/or_00000005
fatcat:xsscmsd33fbyro2qwqauc7umvq