Acute Brucellosis with Myelodysplastic Syndrome Presenting as Pancytopenia and Fever of Unknown Origin

Jun-Jie Li, Zi-Ke Sheng, Sheng Tu, Sheng Bi, Xiao-Min Shen, Ji-Fang Sheng
2012 Medical Principles and Practice  
A 70-year-old woman who had spent 10 days in the local community hospital was referred to our hospital with a 20-day duration of fever ( 1 39 ° C), night sweats, chilling, weakness, weight loss, paleness and pancytopenia, without jaundice and hepatosplenomegaly. Otherwise, she was healthy and without a history Abstract Objective: To report a rare case of brucellosis with myelodysplastic syndrome (MDS). Clinical Presentation and Intervention: A 70-year-old woman presented with pancytopenia and
more » ... pancytopenia and fever of unknown origin (FUO). The initial diagnosis was brucellosis; the woman was treated with doxycycline and rifampin against Brucella melitensis but was later diagnosed as suffering from MDS. She was immediately transferred to the Department of Hematology for further evaluation. Conclusion: This study highlights the rarity of brucellosis with MDS, and we recommend that brucellosis with MDS be considered in patients presenting with pancytopenia and FUO.
doi:10.1159/000333698 pmid:22133749 fatcat:kcljs5zfyncitnrnhvexslw7he