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1 to <S millions of red corpuscles per cubic millimeter instead of the customary 5 millions. The same facts have since been observed over and over again. But how are they to be interpreted? Are we confronted, in this interesting finding at higher altitudes and their accompanying rarefied atmospheres, with an actual new formation of corpuscles? If so, this is a unique illustration of the adaptive response of the organism to the necessities imposed by the diminished oxygen tension. Thisdoi:10.1001/jama.1913.04350040050020 fatcat:7befqwfg7rauxplhi3lxu2ypou