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RNAi Targets in Agricultural Pest Insects: Advancements, Knowledge Gaps, and IPM
Frontiers in Agronomy
The unprecedented target-specificity of double-stranded RNA (dsRNA), due to its sequence-specific mode of action, puts dsRNA at the forefront of biosafe insecticide technology. Since 2007, sensitive target genes have been identified in numerous crop pest insects, with an end goal of applying RNA interference (RNAi) in pest management. Key RNAi targets identified include genes involved in (1) feeding and digestion, (2) production of dsRNases, (3) resistance to insecticides and plantdoi:10.3389/fagro.2021.794312 fatcat:k7rrby5vtnh2tk7ptn54vufllm