A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf
.
AbPredict 2: a server for accurate and unstrained structure prediction of antibody variable domains
2018
Bioinformatics
Methods for antibody structure prediction rely on sequence homology to experimentally determined structures. Resulting models may be accurate but are often stereochemically strained, limiting their usefulness in modeling and design workflows. We present the AbPredict 2 web-server, which instead of using sequence homology, conducts a Monte Carlo-based search for low-energy combinations of backbone conformations to yield accurate and unstrained antibody structures.
doi:10.1093/bioinformatics/bty822
pmid:30951584
pmcid:PMC6542689
fatcat:fqtkv4lmtngc5njccmzpqbvvqy