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Corresponding author: D J J Muckart (firstname.lastname@example.org) The acute coagulopathy of trauma is a complex pathophysiological state that may be initiated by a number of factors. As an integral part of the 'deadly triad' , it may be perpetuated by concomitant acidosis and hypothermia;  excessive pre-hospital fluid resuscitation may lead to haemodilution of clotting factors and worsening of the coagulopathy; and exposure of tissue factor when endothelium or brain matter is denuded results indoi:10.7196/sajs.1665 pmid:23941752 fatcat:hpr7rxhch5cbrfwltqgrzs75hu