On Certain Forms of Non-Puerperal Uterine Haemorrhage

A. E. A. Lawrence
1878 BMJ (Clinical Research Edition)  
THE BRITISH MEDICAL _OURNAL. 93 attention to the subject; and I should not have ventured to do so, had I not satisfied myself of the value of the observAtiolS by the most careful examination of the two tumours and the sprouting masses found in the ascitic fluid in the cases which I have recordedl. Since those two cases, I have had many opportunities of verifying my observations. Later investigations have convinced me that, while it is quite true that particles of sprouting epithelium do
more » ... ithelium do occasionally escape from ovarian tumours and grow on the surface of the peritoineum, after the manner of skin-graftiitg, yet it is eiqually true that masses of sprouting cells may grow from the peritoneum directly, as the result of chronic irritation, caused by a growing ovarian tumour, or by fluids which have escaped from ovarian cysts, and that even the pleural mnembrane may become inivolved in the irritation. One cannot help recalling to recollection the beautiful plates of Klein, wherein he represents the little outgrowths from the peritoneum which appear as the result of chronic irritation of that structure. The microscopical appearance of these outgrowths resemble in a remarkable manner that of the masses of sprouting cells which I have so frequently found in ascitic fluid surrounding sarcomatous tumours of the ovary, and that of the nodules on the peritoneum. In my paper on the Development of the Ova and the Structure of the Ovary, I showed that the ovary is not invested by the layers of the broad liaament, as is. described in many books, but that the stroma of the ovary is derived from, and is directly continuous with, the layers of the broad ligament,
doi:10.1136/bmj.2.916.93 fatcat:pxsetbmlwjejpkpq6airnwkw24