THE SIGNIFICANCE OF THE HIV RESISTANCE ANALYSIS IN ANTIRETROVIRAL THERAPY

D. E. Valutite, Yu. V. Ostankova
2019 Infekciâ i Immunitet  
The methodological pipeline described here is adequate to characterize in-depth mutant spectra of HCV populations, and it provides a tool to understand HCV diversification and treatment failures. The pipeline can be periodically extended in the event of HCV diversification into new genotypes or subtypes, and provides a framework applicable to other RNA viral pathogens, with potential to couple detection of drug-resistant mutations with treatment planning.
doi:10.15789/2220-7619-2018-4-7.17 fatcat:lc7u3crzajglvckr5gco4jko7u