Photodynamic therapy for basal cell skin cancer ENT-organs

V. N. Volgin, E. F. Stranadko, R. V. Kagouants, M. A. Kabanova
2014 Biomedical Photonics  
Results of photodynamic therapy in 96 patients with primary and recurrent basal cell skin cancer of ENT-organs are represented. For photodynamic therapy the Russian-made photosensitizer Photoditazine at dose of 0.6–1.4 mg/kg was used. Parameters were selected taking into account type and extent of tumor and were as follows: output power – 0.1–3.0 W, power density – 0.1–1.3 W/cm2, light dose – 100–400 J/cm2. The studies showed high efficacy of treatment for primary and recurrent basal cell skin
more » ... ancer of nose, ear and external auditory canal – from 87.5 to 94.7% of complete regression. Examples of efficacy of the method are represented in the article. High efficacy and good cosmetic effects allowed to make a conclusion about perspectivity of photodynamic therapy for recurrent basal cell skin cancer of ENT-organs.
doaj:68ab695386f14098a7725f02244a3f8f fatcat:4zxwpn7xsrdslkp7uky7z324e4